Preparative Chromatography
Verlag | Wiley-VCH |
Auflage | 2020 |
Seiten | 620 |
Format | 18,9 x 25,2 x 3,3 cm |
Gewicht | 1397 g |
Artikeltyp | Englisches Buch |
ISBN-10 | 3527344861 |
EAN | 9783527344864 |
Bestell-Nr | 52734486A |
The third edition of this popular work is revised to include the latest developments in this fast-changing field. Its interdisciplinary approach elegantly combines the chemistry and engineering to explore the fundamentals and optimization processes involved.
Inhaltsverzeichnis:
INTRODUCTION
FUNDAMENTALS AND GENERAL TERMINOLOGY
Principles of Adsorption Chromatography
Basic Effects and Chromatographic Definitions
Equilibrium Thermodynamics
Fluid Dynamics
Mass Transfer Phenomena
References
STATIONARY PHASES AND CHROMATOGRAPHIC SYSTEMS
Column Packings
Selection of Chromatographic Systems
References
CHROMATOGRAPHY EQUIPMENT: ENGINEERING AND OPERATION
Introduction
Challenges for Conceptual Process Design
Engineering and Operational Challenges
Commercial Chromatography Column
Commercial Chromatography Systems
Standard Process Control
Packing Methods
Process Troubleshooting
Disposable Technology for Bio-separations
References
PROCESS CONCEPTS
Discontinuous Processes
Continuous Processes
Choice of Process concepts
References
MODELING AND MODEL PARAMETERS
Introduction
Models for Single Chromatographic Columns
Modeling HPLC Plants
Calculation Methods
Parameter Determi nation
References
MODEL BASED DESIGN, OPTIMIZATION AND CONTROL
Basic Principles and Definitions
Isocratic Batch Chromatography
Gradient Batch Chromatography
Recycling Chromatography
Conventional Isocratic SMB Chromatography
Isocratic SMB Chromatography under Variable Operating Conditions
Gradient SMB Chromatography
Practical Approaches for Design of SMB Chromatography
Process Configuration and Optimization by Superstructures
Advanced Process Control
References
Rezension:
"I would not hesitate to recommend it to anyone working in this field."
Chromatographia
"Overall the coverage is a bit uneven - nevertheless the volume does compile some useful material... In conclusion, this is a comprehensive reference text, which should find its way into the libraries of all companies who are serious about process scale preparative chromatography, whether internally or via outsource contracts."
Organic Process Research and Development
"This special volume is essential for chemists and engineers working in chemical and pharmaceutical industries, as well as for food technologies, due to the interdisciplinary nature of these preparative chromatographic processes."
Advances in Food Sciences