Biochemistry and Molecular Biology

The ideal text for any bioscience student encountering biochemistry and molecular cell biology for the first time. Exceptionally clear explanations, frequent diagrams, and a user-friendly design and layout ensure that the text provides a perfect introduction to this complex yet fascinating subject area.

Now in its sixth edition, Biochemistry and Molecular Biology provides the perfect balance between detail and conceptual understanding. Maintaining the much-praised clarity of previous editions, this edition incorporates both new techniques and pivotal discoveries in a succinct, easy-to-digest way, using updated figures and diagrams to help explain complex processes.

Updated content on the manipulation of DNA and genes reflects the rapid introduction of new methods in contemporary research, and incorporates up-to-date discussions of recent developments such as gene editing. Chapter summaries are logically laid out, forming bulleted lists which provide students with a consolidation of difficult concepts and progressively guide them through the specifics whilst keeping the big picture in mind. Additional 'find out more' sections provide helpful problem-solving support and the further reading is divided into types to cater for broader learning needs.

With an integrated a pproach covering both biochemistry and molecular biology, complemented by frequent diagrams and clear explanations, and all presented in a wider cellular context, this text is the perfect introduction for any student new to the subject.

Online Resources:
The online resources to accompany this text include:

For registered adopters of the book:
· Figures from the book available to download

For students:
· Further reading organised by chapter
· An extensive bank of multiple-choice questions to support self-directed learning
· Links to 3D molecular structures in Protein Data Bank

Inhaltsverzeichnis:

Part 1: Basic concepts of life
1: The basic molecular themes of life
2: Cells and viruses
3: Energy considerations in biochemistry
Part 2: Structure and function of proteins and membranes
4: The structure of proteins
5: Methods in protein investigation
6: Enzymes
7: The cell membrane and membrane proteins
8: Muscle contraction, the cytoskeleton, and molecular motors
Part 3: Metabolism and Nutrition
9: General principles of nutrition
10: Food digestion, absorption and distribution to the tissues
11: The storage fuels: Mechanisms of transport, storage, and mobilization of carbohydrate and fat
12: Principles of energy release from food
13: Glycolysis, the TCA cycle, and the electron transport system
14: Energy release from fat
15: An alternative pathway of glucose oxidation: The pentose phosphate pathway
16: Synthesis of glucose (gluconeogenesis)
17: Synthesis of fat and related compounds
18: Nitrogen metabolism: amino acid metabolism
19: Nitrogen metabolism: nucleotide metabolism
20: Mechanisms of metabolic control and their applications to metabolic integration
21: Raising electrons of water back up the energy scale: photosynthesis
Part 4: Information storage and utilization
22: The genome
23: DNA synthesis, repair and recombination
24: Gene transcription
25: Protein synthesis and controlled protein breakdown
26: Control of gene expression
27: Protein sorting and delivery
28: Manipulating DNA and genes
Part 5: Cells and tissues
29: Cell signalling
30: The cell cycle, cell division, cell death and cancer
Part 6: Protective mechanisms against disease
31: Blood clotting, xenobiotic metabolism, and reactive oxygen species
32: The immune system